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Description
In late-stage type 2 diabetes mellitus (T2DM), impaired islet cell function leads to absolute insulin deficiency, thereby disrupting blood glucose homeostasis
Although lipid profiles, HbA1c, and FBG were unaffected, GLP-1 RA was linked to a slight reduction in SBP (SMD 0.20
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Certainly, the apparent advantage of tirzepatide, a dual incretin agonist, over GLP-1RA will spark renewed interest in the therapeutic potential of GIP in type 2 diabetes, obesity and related co-morbidities.
