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10.1016/S0140-6736(21)02188-7 19 DiamantM.NauckM

For Fatigue and Headaches Ensure adequate caloric intake fatigue often results from reduced eating rather than the drug itself
Allow at least 15 to 30 minutes if the vials have been in a -20C freezer

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While genetic variants (such as GLP1R rs6923761) do not predict exact medication response, they can help your provider interpret whether suboptimal clinical results stem from genetic factors, dosing, or potential storage/formulation issues

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