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Typically, these medications are administered once a week through a subcutaneous injection

Risk factors include age (usually affects people over 50), diabetes, hypertension, high cholesterol, sleep apnea, and anatomical predispositions such as a small cup-to-disc ratio

Superior efficacy of insulin degludec/liraglutide versus insulin glargine U100 as add-on to sodium-glucose co-transporter-2 inhibitor therapy: a randomized clinical trial in people with uncontrolled type 2 diabetes

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Many GLP-1 users report reduced appetite, smaller meals, and digestive changes

Among people with no prior substance use disorder, those taking GLP-1 drugs had an 18% lower risk of developing alcohol use disorder, a 25% lower risk of opioid use disorder and an approximately 20% lower risk of cocaine and nicotine dependence