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Early and mid-stage trial results can provide useful signals, but they are not the same as long-term post-approval safety data

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The vagus in turn stimulates second order neurons in the NST (128, 129), located in the medulla of the brainstem ( Figure 1 )

It is a glucagon-like peptide-1 receptor agonist (GLP-1 RA) that was initially developed to treat type 2 diabetes