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The diet-derived short chain fatty acid propionate improves beta-cell function in humans and stimulates insulin secretion from human islets in vitro

Exendin-4, a glucagonlike peptide-1 receptor agonist, attenuates breast cancer growth by inhibiting NF-B activation

10.1073/pnas.1218051109 67 KleinS.SheardN

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Patients with a history of allergic reactions or sensitivities to GLP-1 receptor agonists, pancreatitis, thyroid cancerincluding medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN-2) generally are not suitable candidates for this therapy