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In some of the studies, an additional 10% dose reduction was done with drug escalation

Lets now look in detail at how does Wegovy work

That said, some patients report throat discomfort after experiencing severe nausea or vomiting during their first dose adjustments

The safety of GLP-1RAs and GLP-1/GIP dual agonists during pregnancy constitutes a significant area of concern, especially regarding the management of diabetes and obesity in this population

It also shows that its safe for patients to use as a medical provider

So, if you want more GLP-1, you want to encourage the growth of the bacteria that produce butyrate, and one of those bugs is called Akkermansia