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The glucagon-like peptide-1 receptor (GLP-1R) plays a central role in metabolic regulation and is a major therapeutic target for obesity and diabetes

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Long-term semaglutide use for weight management shows generally favorable safety data in clinical trials, though individual outcomes depend on baseline health status, existing conditions, and genetic predispositions

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A hiatal hernia occurs when a portion of the stomach pushes through the diaphragm into the chest cavity

Educational reference.