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People who are very lean in the abdominal area, particularly men with low body fat percentages, may find this site less comfortable and should consider the thigh as their primary site instead

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Those taking warfarin should exercise caution and monitor INR levels when starting or stopping probiotics, as some bacterial strains might theoretically affect vitamin K production, though evidence is limited and this concern does not apply to direct oral anticoagulants (DOACs)

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