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In 1 study, nearly 50% more women discontinued the treatment compared to men, though this difference did not reach significance in this study, which was not powered for sex difference detection (78)

It mimics a natural hormone called glucagon-like peptide-1 that your body releases after eating

Rodent studies have demonstrated that, upon GIP stimulation, the nervous system promotes GLP-1 secretion from L cells, which express the receptors involved in neuronal signalling 26,27

Genetically predicted lower BMI via GLP-1R activation was associated with better well-being, including better life satisfaction, lower neuroticism, fewer depressive symptoms, and greater positive affect

Thats tens of millions of used needles entering the waste stream every year

Mounjaro (tirzepatide): Has a half-life of about 5 days, meaning it could take 4-6 weeks to be eliminated