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One concern exists

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These patients were administered escalating weekly doses of semaglutide (1 mg)

Carlezon WA, Bguin C, DiNieri JA, Baumann MH, Richards MR, Todtenkopf MS et al (2006)

Clinical trials indicate that tirzepatide surpasses the weight loss achieved with some other GLP-1 receptor agonists

Exenatide inhibits necrosis by enhancing angiogenesis and ameliorating ischemia/reperfusion injury in a random skin flap rat model
