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This is novel compared to older agents that targeted just one pathway

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doi: Mozaffarian D

Third, real-world data from large patient populations suggests GLP-1 receptor agonist users may have lower rates of certain inflammatory conditions
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Semaglutide can also improve heart failure-related symptoms and inflammation in patients with obesity-related heart failure with preserved ejection fraction (HFpEP), and decrease the risk of major kidney disease events and cardiovascular-related mortality in patients with type 2 diabetes and chronic kidney disease(Butler et al 2024
