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stopping often leads to weight regain

While there are a plethora of factors that come into play in losing weight (sleep, activity, medications, health conditions...), experts tend to agree that on the surface, a calorie deficit is one of the simplest and most effective strategies for weight loss

Common side effects include nausea, vomiting, diarrhea, and constipation, which typically diminish with dose adjustment

KAZN/C1ORF196 was identified by Le Pennec et al