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Description
Slowing gastric emptying: GLP-1 agonists delay the rate at which the stomach empties its contents into the small intestine

Younes et al

Side Effects: From Sleepiness to Stomach Trouble Not everyone simply feels nothing

The Egger test for these outcomes indicated some asymmetry for CV death only (P = 0.10)

Another critical difference: older drugs had minimal metabolic benefits beyond appetite suppression, whereas GLP-1 medications improve insulin sensitivity, reduce inflammation, and show cardiovascular protection independent of weight loss alone

Ozempic and Wegovy both use semaglutide, but Ozempic is labeled for diabetes and Wegovy for weight loss, which shapes what insurance will cover and at what dose
