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The drugs connected to these injuries include Ozempic, Wegovy, Rybelsus, and Saxenda (made by Novo Nordisk) and Mounjaro, Zepbound, and Trulicity (made by Eli Lilly)

Third -- and most relevant to the GLP-1 conversation -- some olive-derived compounds appear to stimulate the very same gut hormone pathways that GLP-1 drugs target pharmacologically

doi: 10.1677/joe.1.07070

Recent studies have found that increased level of GLP-1 in the hippocampus restores GABA and reverses this neurotoxic effect by reducing oxidative stress through the SIRT1/Nrf2/HO-1 pathway, promoting autophagy through the AMPK/mTOR pathway, and alleviating hippocampal apoptosis by inactivating pro-apoptotic kinase GSK-3 ( The anorectic effects of GLP-1 can also be explained by its GABAergic modulation in the nucleus tractus solitarius (NTS) cells

GLP-1s may start the process, but the body heals when we support it with real food, movement, Redox balance and healthy routines

Semaglutide as a therapeutic option for elderly patients with type 2 diabetes: Pooled analysis of the SUSTAIN 15 trials