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When added together, the effects may lead to worse nausea, vomiting, or unexpected changes in blood sugar

Nausea severity typically peaks within days and gradually resolves over 12 weeks as the body adapts

Other potential side effects of semaglutide injections include burning at injection sites on the skin, blistering, discoloration of the skin or yellow patches in your eyes or mouth, hives, infection, inflammation, itching sensation, lumps under the skin where you injected called lipohypertrophy, numbness around the lips and regions close to them due to injections too often in one area, pain or soreness around the injection site that lasts longer than 24 hours after injecting yourself with semaglutide which could last several days and rashes

Over time, this leads to consistently higher drug levels, more side effects, and a pattern that can mimic overdosing

Sending thanks from our family, including Smokey and Floozy

Where relevant, transfection was performed as for functional assays and surface labelling of SNAP-tagged GLP-1R was performed using 0.5 M of the indicated SNAP-Surface probe for 30 min at 37C before washing with HBSS