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Today, more people than ever before are facing the challenges of obesity, diabetes, and arthritisoften all at the same time

If that feels stable, a 14/10 schedule may be a reasonable next step

Deal trajectory: Lilly closed a $1.3B preclinical obesity deal with Nimbus Therapeutics (Jan 2026) for an oral small molecule targeting a novel mechanism, plus a muscle-sparing obesity deal with a Chinese biotech (Nov 2024)

(2023, October 5)

Once the poster child for the category, it appears the years of double digit yearly gains are coming to an end for the Danish company, with 2026 sales expected to fall between 5% and 13%

Stepping back a tier and spending two extra months building tolerance before re-escalating produces better long-term outcomes than powering through three weeks of daily nausea