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Dual agonists target both the GLP-1R and another specific receptor, such as GIP (glucose-dependent insulinotropic polypeptide) or IGF (insulin-like growth factor) receptors
But it should only be used under medical supervision

"Our clients serve the patients who fall through the cracks - people for whom this medication isn't optional, it's essential." The brief argues that FDA's decision was procedurally flawed, substantively unsupported, and dangerously out of step with real-world healthcare delivery
While they are highly effective for blood sugar control and appetite regulation, many patients experience unexpected digestive side effects

Those with past allergic reactions to GLP-1 receptor agonists should also consult their healthcare provider before starting treatment
