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In experimental models of obesity, agonism of GLP-1 receptors can improve cognitive deficits and depression with the activation of mTOR and the inhibition of autophagy [54]

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Slater is the chair of the SAGES Guidelines committee and has received consulting fees from Hologic

GLP-1 Agonists Like Semaglutide Show Promise in Reducing Alcohol Use Disorder, Study Finds Feb 20, 2025 2 min read Updated: Nov 6, 2025 Recent research suggests that semaglutide, a medication primarily used for type 2 diabetes and weight management, may also help reduce alcohol consumption

In an extensive retrospective study, semaglutide 2.4 mg OW was found to be more effective than liraglutide 3.0 mg daily in treating weight regain after bariatric surgery, achieving greater total body weight reduction and improved tolerability [194]