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WHY A LOADING DOSE APPROACH IS NOT ROUTINE Antidepressants begin affecting neurotransmitter systems soon after initiation, but full therapeutic effects may not appear for weeks and depend on downstream neurobiologic changes

[8] Therefore, MBs MAO-inhibiting property, while mechanistically interesting and potentially therapeutic in some contexts, necessitates extreme caution to avoid adverse drug interactions (see Interactions)
This led to its FDA approval for heart disease prevention
Recent research progress on the evidence and mechanism of cardiovascular benefit of SGLT2 inhibitors in type 2 diabetes mellitus population

They do not reverse thyroid tissue damage
