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Due to massive and persistent cultural and patient resistance and restrictive regulations, opioid-based OUD treatments like methadone and buprenorphine are used by a small fraction of people who could benefit from them

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The takeaway here is that regardless of BMI or body shape, focusing on building and maintaining muscle is the bedrock of sustaining long-term cardiometabolic health

The plan might include gradually de-escalating the medication dose, considering alternative medications, intensified lifestyle support and more frequent check-ins