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This situation translated into an increased OARSI score, increased secretion of TNF-, increased expression of MMP-13 and COLX and bone marrow lesions [47]

Activation of murine preproglucagon-producing neurons reduces food intake and body weight

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Bariatric surgery and prevention of type 2 diabetes in Swedish obese subjects

Since glucagon tells the liver to release stored sugar into the blood, suppressing it helps keep blood sugar levels stable, preventing the "crashes" that often lead to overeating and weight gain
