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The TRIUMPH-4 Phase 3 trial showed retatrutide reduced knee pain by 75.8% in participants with obesity and osteoarthritis a finding that reframes this peptide as a joint health therapy, not just a weight loss drug.

The aim of this narrative review is to critically assess the renoprotective effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in managing albuminuria among patients with type 2 diabetes mellitus within the framework of personalized ...