glp-1 agonists oral Peptide receptor agonists: From injection to delivery strategies Oral GLP-1 receptor agonists are
Description
Oral drugs do away with several of the drawbacks that are associated with injectable drugs, such as needle fear and difficulties with administration
The main enzyme involved, dipeptidyl peptidase-4 (DPP-4) also known as CD26, cleaves off the two N-terminal residues resulting in GLP-1 (9-36 amide) which is inactive or acts as an inhibitor at the GLP-1 receptor (23)
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