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Participants were excluded if they used these drugs in the year before enrolment or had contraindications to them
Two randomized, placebo-controlled studies have evaluated the efficacy of GLP-1 analoguesexenatide and dulaglutideon alcohol consumption outcomes in adult participants, offering distinct, but complementary perspectives on their utility in addiction medicine
In wildtype but not GLP-1R KO mice, liraglutide stimulates the secretion of natriuretic peptide (ANP) from the atrial cardiomyocytes and liraglutide fails to affect natriuresis and vasorelaxation in mice deficient for ANP [640]
In addition, a large-scale clinical study demonstrated that GLP-1 analogues could reduce the mortality of patients with prostate cancer and diabetes (210, 224)
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