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These symptoms are associated with several health-related issues such as: Chemotherapy and radiation treatment Medications Alzheimers, Dementia, ParkinsonsDisease Dry mouth Autoimmune diseases, Sjgrens Disease, Arthritis COVID-19 symptoms (loss of taste and dry mouth) Why Is Metallic Taste A Problem? Metallic taste is usually a side effect due to chemotherapy, radiation treatments, medications, and central nervous system disorders. Metallic or altered tastes can leave people feeling oral discomfortand may cause poor nutrition