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In cigarette smokers, seminal and serum levels of cotinine and 3HC appear to be similar, whereas seminal nicotine levels are generally higher than serum levels [22]

For cases due to excessive alcohol consumption, a person immediately needs to stop drinking alcohol and switch to clear fluids

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Future directions: e-cigarette and microbiome Many studies have demonstrated that e-cigarettes altered the microbiome composition of respiratory tracts such as the nasal passages, mouth, and lungs, as well as the gut microbiota [83, 84, 98,99,100]

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