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RELATED: How many Chromosomes do Humans have Table of Contents When nicotine is ingested, it quickly enters the bloodstream and travels to the brain, where it stimulates the release of the neurotransmitter dopamine, which produces a pleasurable sensation commonly referred to as a nicotine high. This effect is what makes nicotine highly addictive, and it can be difficult for people to quit using nicotine products once they become addicted

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