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Concerns around ETS have played a central role in the debate over the harms and regulation of tobacco products because of its harm to by-standers especially woman and children.87 Most of the studies involved the effects of ETS on fertility focused on females because of their susceptibility to ETS and the direct impairment to impregnation and embryonic development.88 Intrauterine exposure to environmental toxic substances in pregnancy has the potential to cause adverse effects on the prenatal development of the embryo