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For the general public, these results could help them to better understand the risk of smoking and manage their health 189

Additionally, smoking accelerates the ageing process, causing premature wrinkles and age spots, which can contribute to an overall darker or more uneven skin tone

4,5,6 During manufacturing, ammoniaa chemical found in household cleaning productsalong with other chemicals may be added to increase nicotine absorption

For ease of communication, we further classified each smokingoutcome association into a star rating from 1 to 5

Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines 31 for each of our systematic reviews, we identified studies reporting relative risk (RR) of incidence or mortality from each of the 36 selected outcomes for smokers compared with nonsmokers

The effect of cigarette smoking on the oral and nasal microbiota