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Tobacco smoking affects the serum levels of many coadministered drugs due to induction of cytochrome P450 (CYP) hepatic enzymes (especially CYP1A2) by polycyclic aromatic hydrocarbons and non-nicotinic chemical constituents, resulting in more rapid metabolism and clearance of certain drugs

What matters far more than counting puffs is choosing the right nicotine strength for your old habit

Nicotine impersonates the neurotransmitter acetylcholine (ACh), and by binding to receptors ACh would usually bind to, stimulates the production of dopamine, which is involved in your bodys reward pathways

The main active chemical in marijuana is delta-9-tetrahydrocannabinol, or THC

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Starting with one cigarette and assessing your response before consuming more is always recommended