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Women in the age group of 20-24 had a 11% chance of a spontaneous miscarriage, while women in the age group of 40-44 had a 51% chance..The problem is graver than that, added Dr Rao, specifying that couples who smoke and have a child, create weaker progeny who is more susceptible to cancer, while fragmented DNA can cause other health issues in the child such as mental and physical retardation..People should be asking themselves about just what it is they are trying to create a next generation that will be immunologically weak? he said..Dr Rodrigues specified that fragmented sperm is not a permanent problem