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If more participants had been able to adhere to the intervention, the per-protocol analysis would have carried greater precision in estimating the true impact of the pack size

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Similar trends were seen for Mori who currently smoke (Figure A1 in the Appendix) though the drop in prevalence in the 2022/23 survey was less pronounced for this measure (from 22.3% to 20.2%, 2.1% absolute drop)

Animal models have also demonstrated that PNE alters the development of the mesocorticolimbic system which is important for goal-directed behavior and its ability to modulate neural processes that contribute to drug abuse [166]

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