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Microglia as Therapeutic Target for the Treatment of Nicotine Addiction We speculate that neurodevelopmental changes may be modulated by pharmacotherapy targeted to activate change in microglial phenotype which may promote brain homeostasis and a neuro-adaptation that favors decreased dependence on nicotine thus microglia are a promising therapeutic target that need to be explored

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doi: 10.1136/tobaccocontrol-2018-054325 [DOI] [PMC free article] [PubMed] [Google Scholar] 7.Rahman S, Engleman EA, Bell RL