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When cannabis is inhaled, THC reaches the bloodstream very quickly and then usually decreases over 34 hours as it is absorbed by body tissues

10.1371/journal.pone.0182998 8 AmereG

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Within 20 minutes of smoking your last cigarette, your body begins a series of changes that continue for years

CYP2B6 and bupropion's smokingcessation pharmacology: the role of hydroxybupropion