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It refers to the compulsive consumption of tobacco products, such as cigarettes, smokeless tobacco, or chewing tobacco, driven by cravings and withdrawal symptoms when not using

The major strength of this study was the collection of detailed information on smoking habits at each of seven examination rounds during 40 years of followup

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Observational studies try to adjust for these things, but they cannot magically remove every hidden bias

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Raw, Smuggling and Cross-border trade of tobacco in Europe," British Medical Journal 3, (1995): 1393-7 ( [18] HMRC Annual Report 2005-06 and Autumn Performance Report, 2006, 30, [19] Sophia News Agency, "Bulgarian FC President Arrested in Greece over Cigarette Smuggling in UK," Sophia News Agency, Bulgaria, [20] HMRC Departmental Report: Integrating and Growing Stronger, Spring 2007, 39, [21] Lindquist Avey, Macdonald Baskerville, Forensic Financial Investigations, Cigarette Smuggling in the State of Michigan , August 15, 1994