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Am J Addict 2016;25:2916

Retrieved July 14, 2015, from Mayo Clinic Staff

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Natural wrappers are lighter in color and generally have a milder flavor, while Maduro wrappers are darker with a richer flavor profile

The two produce meaningfully different exposure patterns: retrohaling exposes your nasal passages to exhaled vapor that has already passed through the respiratory system, while a nose vape introduces fresh aerosol concentrate directly into the nasal cavity

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