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In the United States, the political clout of Big Tobacco stalled reforms for decades

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The tumour revealed itself gradually, pale and soft against the normal architecture of the brain

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Prior research using tobacco industry documents has demonstrated how companies have sought to create brand identities that have value for populations with relatively low power (women, poor, racial minorities) in conveyance of attainment of aspirational status or lifestyles (Anderson, Glantz and Ling 2005
This cellular damage activates hepatic stellate cells (HSCs), which are key players in liver fibrogenesis, contributing to the deposition of extracellular matrix proteins and the progression of fibrosis [8,9,10]
