cigarette smoke induces cytoplasmic p53 accumulation Tobacco carcinogens, DNA damage and mutations in smoking-associated cancers The role of p53-mediated signaling

This inhibition of AKT/mTOR, in combination with transactivation of damage-regulated autophagy modulators, guides the p53-mediated elimination of damaged cellular components by autophagic clearance

The effects of several agents affecting the p53-related pathways on male infertility are shown in Table 2

[DOI] [PubMed] [Google Scholar] 2.Sun X., Zhang N., Yin C., Zhu B., Li X

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Interestingly, maternal smoking has been found to disproportionately affect male fetal growth compared to female fetal growth (Zaren et al., 2000)

Compared with the control group, the -galactosidase positive rate in CTPB group is higher, which may be related to CTPB increasing the relative expression of p300 protein and promoting the aging of EPCs