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Whilst adjustments for multiple testing reduce type one error rates (the rate of falsely finding a significant result), they simultaneously increase type two error rates (the rate of falsely concluding a null result), which increases the likelihood of missing important findings

But the melanin overproduction pathway is fully active

} : CS1 maint: DOI inactive as of July 2025 (link) "Arsenic Exposure Induces the Warburg Effect In Cultured Human Cells"