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After activation, Nrf2, a nuclear factor, can induce MDM2-mediated Rb proteosomal degradation by promoting MDM2 expression, which might block the Rb/E2F pathway that mediated the inhibitor of cell-cycle progression of infected hepatocytes 82
Carbon monoxide an odorless, colorless, and poisonous gas is released into the body when a person smokes
Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development
Recently, epigenetic changes have been proposed as possible alternative causes of some diseases
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Li-Fraumeni and related syndromes: correlation between tumor type, family structure, and TP53 genotype
