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Antiplatelet drugs The thienopyridine P2Y12 inhibitors clopidogrel and prasugrel are converted to their active metabolites by CYP isoenzymes, including CYP1A2, CYP2B6, CYP2C19, CYP3A4/5 and CYP2C9, thus enzyme induction by smoking could theoretically increase the antiplatelet activity of these agents

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Join the conversation Yet for many patients, pregnant or not, quitting smoking remains difficult, Horsager-Boehrer said

Tom Petty photographed by Allan Tannenbaum- New York City, 1977 Tom Petty and the Heartbreakers@tompettyTom Petty photographed by Allan Tannenbaum- New York City, 19774:06 AM Jan 28, 20211901910801081.2K01.2K606Read 19 replies

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In the committees opinion, the data suggest that the Surgeon Generals 1964 report and the dissemination of information on the adverse health effects of smoking had a strong impact on smoking prevalence