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This, of course, is due to his being a confirmed cigarette fiend [n]o doubt the defense will be insanity, caused by the excessive use of the deadly cigarette. One of the most publicized cigarette fiend cases was that of 16-year-old Charles Cross

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However, for those who smoke regularly, the throat may not have sufficient time to recover, which leads to prolonged or recurring discomfort

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Estrogen influences how the brain interprets sensory information, including smell

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