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Using a mouse model of Alzheimers disease, researchers gave one group of mice free access to food throughout the day but fed another group on a time-restricted schedule (limited to a six-hour window each day), translating to about 14 hours of fasting for humans

Proposed Mechanism of Action AOD-9604's proposed mechanism centers on selective activation of lipolytic pathways in white adipose tissue

Fernandes CG, da Rosa MS, Seminotti B et al (2013) In vivo experimental evidence that the major metabolites accumulating in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency induce oxidative stress in striatum of developing rats: a potential pathophysiological mechanism of striatal damage in this disorder

Each fourth seedling leaf was collected for subsequent experiments

What the evidence does not yet support Here is where honesty matters most

doi: 10.1042/bj3280099