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Immunofluorescence staining similarly revealed that the expression of PHB2, BECN1, and LC3 was significantly decreased in HG of the aged mice compared to HG of the young mice (Fig

doi: 10.1111/jdv.19717

Taken together, these results demonstrate the power of integrating metabolomic profiling with public databases of cancer dependencies (e.g., DepMap) to identify synthetic lethal vulnerabilities of cancer cells

Structure of GPX4 U46C-R152R is modeled based on PDB structure 2OBI

[DOI] [PubMed] [Google Scholar] Nikaido H
