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Immunofluorescence staining similarly revealed that the expression of PHB2, BECN1, and LC3 was significantly decreased in HG of the aged mice compared to HG of the young mice (Fig

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doi: 10.1111/jdv.19717

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Taken together, these results demonstrate the power of integrating metabolomic profiling with public databases of cancer dependencies (e.g., DepMap) to identify synthetic lethal vulnerabilities of cancer cells

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Structure of GPX4 U46C-R152R is modeled based on PDB structure 2OBI

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[DOI] [PubMed] [Google Scholar] Nikaido H

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