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10.4254/wjh.v12.i5.184 [DOI] [PMC free article] [PubMed] [Google Scholar] Konosic S., Petricevic M., Ivancan V., Konosic L., Goluza E., Krtalic B., et al

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Experiments ex vivo have shown that vinpocetine acts as a selective inhibitor of Ca 2+ /calmodulin-dependent cyclic nucleotide phosphodiesterase type I [21,108], a potent blocker of voltage-gated sodium channels [109,110], inhibits platelet aggregation, reduces blood viscosity, vasodilates cerebral arteries, and increases cerebral blood flow [111]