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Therapeutic strategies for COVID-19: progress and lessons learned
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The injection itself takes 10 to 15 minutes depending on the number of areas being treated
Mapping was performed using the reference genome BDGP6.46, INSDC Assembly GCA_000001215.4 (details provided in Supplementary Data 9)
Probably due to the binding preference of APAP to the active site of each P450 isomer, it is oxidized via two pathways to form the toxic intermediate N-acetyl-p-benzoquinone imine (NAPQI) and the non-toxic catechol metabolite 3-hydroxy-APAP (3-OH-APAP) (Figure 1)
