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Vitamin B12 supplementation is considered safe during pregnancy with no evidence of harm to the developing fetus at recommended doses

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However, there are no relevant research reports on the mechanism of action of GPX6, which may be related to the oxidative stress response involved in glutathione

These proteins share a conserved N-terminal domain capable of forming membrane pores that disrupt cellular integrity, leading to cell swelling, membrane rupture, and release of intracellular contents (73)

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