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Beyond direct Nrf2 activators, other agents operate through complementary pathways: Glutamine alleviates injury by inhibiting the xanthine oxidase/uric acid axis[140], while compounds like agmatine and naringin exert their effects by enhancing cellular glutathione reserves and reducing lipid peroxidation[141, 142]

[DOI] [PubMed] [Google Scholar] 108.Yatin S

Mayo Clinic

Rasagiline can be used as either a monotherapy in the early stages of the disease or as an adjunct therapy in the later stages, whereas selegiline is commonly used as an adjunct therapy to levodopa in the later stages of the condition

NAC and Addiction In preclinical studies, mGlu receptors are promising candidate pharmacotherapeutic targets in the management of substance use disorders [115]

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