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Clinicians must balance providing enough Se to correct deficiencies and prevent toxic effects [28]

For instance, the weakly trans-directing aromatic heterocyclic ligands reduce the kinetic liability of trans chloride groups and thus prevent deactivation by sulfur-rich biomolecules, a common detoxification pathway for cisplatin

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Wu Y, Shi W, Wang H, Yue J, Mao Y, Zhou W, Wang Y

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