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Regarding safety, amantadine is generally well-tolerated, with common adverse reactions including hallucinations, dizziness, and constipation, most of which are mild to moderate [129, 130]

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Functional Roles for Exosomal MicroRNAs in the Tumor Microenvironment

The IC 50 that caused a 50% decrease in cell viability was notably higher (0.41 M for HG-3 cells and 66.2 M for MEC-1 cells) than the concentration of CB-839 required for functional GLS-1 inhibition ( Figure 3A )

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